CMDR: Members

CMDR Members

Robert E. W. Hancock (Director, CMDR) Professor, Dept Microbiology & Immunology, Faculty of Science.	email web page	Pathogenomics. Antibiotic action and resistance mechanisms. Outer membranes of Gram negative bacteria, especially Pseudomonas aeruginosa Cationic Antimicrobial Peptides: Mechanisms of action, development as novel antimicrobials and role in innate immunity.
David P. Speert (Associate Director, Microbial Diseases, CMDR) Professor, Dept. of Pediatrics, Faculty of Medicine.	email web page	Studies of bacterial infection of the lung, particularly in patients with cystic fibrosis. Specfic research projects involve attempts to elucidate virulence determinants of Pseudomonas aeruginosa and Burkholderia cepacia and to clarify the role of macrophages in host defense of the lung
W. Robert McMaster (Associate Director, Immunity, CMDR) Head, Medical Genetics Dept, Faculty of Medicine.	email web page	Immunogenetics, Molecular immunology, Leishmania, Mycobacterium tuberculosis.
Ninan Abraham Asst Professor, Dept Microbiology & Immunology, Faculty of Science.	email webpage	Cytokine regulation of lymphocyte control by signalling pathways that mediate proliferation and survival
Yossef Av-Gay Assoc Professor, Dept. of Medicine, Faculty of Medicine.	email web page	Microbial pathogenicity. Molecular genetics of microorganisms. Identification of targets for drug design.
Fiona S.L. Brinkman (Associate member CMDR) Asst Professor, Dept Molecular Biology & Biochemistry, Simon Fraser University	email web page	Pathogen bioinformatics. Evolution of pathogenicity. Prediction of the subcellular localization of proteins, particularly cell surface-exposed proteins.
Robert C. Brunham Director, UBC Centre for Disease Control, Medical Director, BC Centre for Disease Control.	email web page	Epidemiology and immunology of sexually transmitted diseases, especially Chlamydia trachomatis, and their impact on reproduction and genetics.
Janet K. Chantler Associate Professor, Dept Pathology & Laboratory Medicine, Faculty of Medicine	email webpage	Viral pathogenesis and persistence. Rubella and Coxsackie virus B.
Anthony W. Chow Professor, Dept. of Medicine, Faculty of Medicine.	email web page	Molecular pathogenesis/clinical spectrum of staphylococcal toxic shock syndrome. Mucosal immunity of the female genital tract. Heat shock protein gene in microbial identification, phylogeny, pathogenesis and serodiagnosis.
Julian E. Davies Professor, Dept. Microbiology & Immunology, Faculty of Science.	email webpage	Function/regulation of resistance transfer factors. Origin/evolution of antibiotic resistance genes. Antibiotics as effectors of self-splicing reactions. Gene transfer between distantly related microbes. Application of Microbial diversity.
Simon R.M. Dobson Clinical Assoc Professor, Pediatrics Dept., Faculty of Medicine	email	Neonatal infections, study of immunogenicity & vaccine implementation, Hep B & Influenza vaccine studies, infections in childhood.
Vincent Duronio Professor, Dept Medicine, Faculty of Medicine.	email web page	Cytokines and receptors, Signal transduction, Inflammatory cells
Jan Dutz Assoc Professor, Div Dermatology, Faculty of Medicine	email web page	Skin as an immune organ; Transcutaneous immunization, Antigen presentation, Cytotoxic T-cells, Vaccine design, apoptosis and immunity
Brian E. Ellis Professor and Assoc Director, Michael Smith Laboratories and Faculty of Agriculture	email web page	Plant biochemistry and biotechnology.
Rachel Fernandez Assoc Professor, Dept Microbiology & Immunology, Faculty of Science.	email web page	Molecular pathogenesis of Bordetella pertussis.
B. Brett Finlay Professor, Michael Smith Laboratories and Dept Microbiology & Immunology, Faculty of Science.	email web page	Host-parasite interactions. Salmonella as a model intracellular pathogen. Enteropathogenic and enterohemorrhagic E. coli. Epithelial cell signal transduction involved in bacterial invasion. Live oral vaccines.
Erin Gaynor Asst Professor, Dept Microbiology & Immunology, Faculty of Science.	email webpage	Functional pathogenomics of Campylobacter pathogenesis.
Shirley Gillam Professor, Dept. of Pathology and Laboratory Medicine, Faculty of Medicine.	email	Molecular biology of Rubella Virus.
Mike R. Gold Assoc Professor, Dept Microbiology & Immunology, Faculty of Science.	email web page	Signal transduction by the B lymphocyte antigen receptor (BCR).
Mike Grigg Asst Professor, Dept. of Medicine, Faculty of Medicine	email webpage	Toxoplasma pathogenomics
Philip Hieter Director, Michael Smith Laboratories and Professor, Dept. of Medical Genetics, Faculty of Medicine.	email web page	Molecular Genetics. Chromosome transmission. Centromere function. Mitosis. Cell division cycle. Mechanism of aneuploidy. Genome analysis.
Judith L. Isaac-Renton Professor, Dept Pathology & Laboratory Medicine, Faculty of Medicine.	email web page	Tropical diseases and medical parasitology. Pathogenesis, epidemiology and etiology of giardiasis. Cryptosporidiosis and toxoplasmosis.
Francois Jean Director, Laboratory for Antimicrobial Therapy, CIHR/Health Canada Scholar, Asst Professor, Dept Microbiology & Immunology, Faculty of Science.	email web page	Host-virus interactions: Virogenomics and viroproteomics of Flaviviridae (Hepatitis C virus) and Herpesviridae (HHV-6, -7 and 8) and Coronaviridae (SARS-CoV). Identification and development of new protein-based antiviral agents.
Wilf Jefferies Professor, Michael Smith Laboratories and Dept Microbiology & Immunology, Faculty of Science.	web page	Functions of iron transport molecules expressed at the brain endothelium; Viral antigen processing and presentation; Evasion of the host immune system by Human Adenoviruses.
Pauline Johnson Professor, Dept Microbiology & Immunology, Faculty of Science.	email web page	Molecular mechanisms that regulate the T cell immune response, immune cell adhesion and migration at sites of inflammation
Patrick Keeling Assistant Professor & Scholar, Dept. of Botany and Canadian Institute for Advanced Research Faculty of Science	email web page	Evolution of protozoa with emphasis on the origin of intracellular parasites apicomplexa and microsporidia, effects of symbionts on evolution of eukaryotic genomes, and understanding eukaryotic evolution through comparative phylogeny.
Paul Keown Professor & Div. Head, Nephrology, Dept Medicine, Faculty of Medicine	email webpage	Transplantation, Graft rejection, Tolerance, Autoimmunity
James W. Kronstad Professor, Michael Smith Laboratories and Dept Microbiology & Immunology, Faculty of Science.	email web page	Fungal sexual development. Plant-Microbe interactions. Fungal morphogenesis and pathogenicity.
Hannu S. Larjava Professor, Dept Oral Biological & Medical Sciences, Faculty of Dentistry.	email web page	Integrins of wound healing.
George A. Mackie Professor, Dept Biochemistry & Molecular Bioloy, Faculty of Medicine & Assoc VP Academic Planning	email web page	mRNA turnover, ribosomal assembly, and viral replication.
Linda Matsuuchi Assoc Professor, Dept Zoology, Faculty of Science	email web page	Intracellular trafficking and cell signaling of membrane receptors; Structure and function of the antigen receptor on B lymphocytes.
Deborah Money Clinical Instructor	email webpage
Muhammad Morshed Clinical Assistant Professor, Dept Pathology, Faculty of Medicine, and Head, Zoonotic Diseases & Emerging Pathogens, BCCDC	email web page	Helicobacter spp., Borrelia spp., Treponema pallidum, and zoonotic diseases.
Devki Nandan Research Assoc, Dept Medicine, Faculty of Medicine.	email web page	Biochemistry and cell biology of host-pathogen interactions, emphasis on cell-signalling associated events in human macrophages.
Corrine S. L. Ong Asst Professor, Dept Pathology & Laboratory Medicine, Faculty of Medicine.	email web page	Structure, function and purification of immunogenic membrane proteins. Vaccine Immunology. Molecular bio-typing and fingerprinting of endemic/epidemic isolate of protozoans. Gastrointestinal and blood protozoans.
David M. Patrick Assoc Professor, Dept Medicine and Director, Communicable Disease Epidemiology, BC Centre for Disease Control	email webpage	HIV Epidemiology; Sexually transmitted diseases; Control of communicable diseases.
Neil E. Reiner Professor & Division Head, Infectious Diseases, Dept Medicine, Faculty of Medicine.	email web page	Mononuclear phagocyte activation and cell signalling, cellular and molecular aspects of immunoregulation during chronic intracellular infection.
Michael L. Rekart Clinical Assoc Professor, Dept Medicine and Director, STD Clinic, BCCDC	email webpage	HIV; Epidemiology; Screening; Clinical trials.
David W. Scheifele Professor, Dept Pediatrics, & Director Vaccine Evaluation Centre, Faculty of Medicine.	email web page	Vaccine evaluation research; vaccine policy formulation; vaccine program evaluations.
Kirk Schultz Assoc Professor, Dept Pediatrics, Faculty of Medicine	email webpage	Pediatric oncology, Hematopoietic transplantation
Richard W. Stokes Assoc Professor, Dept Pediatrics, Faculty of Medicine.	email web page	Mycobacterial pathogenesis. Interaction of mycobacteria with macrophages. Novel therapeutics for mycobacterial infections.
Natalie C. J. Strynadka Professor, Dept Biochemistry, Faculty of Medicine.	email web page	Antibiotic resistance; LexA repressor; Antibiotic design; Inhibitor Design/BLIP.
Hung Sia Teh Professor, Dept Microbiology & Immunology, Faculty of Science.	email web page	Role of RasGRP1, TNFR2 and CD30 in T cell function; Mechanism of induction of dermatits in a mouse model; Role of self-specific CD8 T cells in regulating tumor growth.
Charles J. Thompson Professor and Head, Department of Microbiology and Immunology, University of British Columbia Life Sciences Centre.	email web page	Regulation of bacterial gene expression. Transcriptional regulators that program antibiotic biosynthesis and resistance in Streptomyces. Innate antibiotic resistance and developmental states in Streptomyces and related Mycobacteria.
VV-Jukka Uitto Professor, Oral Biological & Medical Science, Faculty of Dentistry	email	Studies on collagenolytic activity in periodontal diseases, oral bacteria & eptithelial cell behaviour in wound infection & healing, elastase inhibitors
J. Douglas Waterfield Professor Dept Oral Biological & Medical Sciences, Faculty of Dentistry	email webpage	Pediodontal disease; immunology; Cytotoxic T cells; Systemic Lupus; Erythematosis; Rheumatoid arthritis and Sjorgreus syndrome.
Decheng Yang Assoc Professor, Dept Pathology & Laboratory Medicine, Faculty of Medicine.	email web page	Coxsackievirus replication and pathogenesis. Host gene response to viral infections. Development of anti-virus drugs and DNA vaccine of enterovirus.

Updated March 2008